AppliFlex ST

With the AppliFlex ST single-use mini bioreactor, we are introducing the same flexibility of our customizable range of glass and stainless-steel bioreactor systems from lab to full production scale, to the single-use lab scale bioreactor market. Applikon offers tailor-made and fully reproducible solutions with 500 mL single-use bioreactors. By using 3D manufacturing technology, we create single-use bioreactors that are beyond your imagination.

  • Pre-assembled, pre sterilized and ready to go bioreactor, saving time and effort
  • Fully customizable to meet your bioprocessing needs
  • Optimize the bioprocessing hardware at small scale
  • Combine with our control, PAT and PIMS solutions for maximum information extraction from your process
  • Compact footprint for maximum use of your bench space

The Single-Use design offers fast start-up of your process.The system is supplied gamma radiated and ready to go with all tubing and connections. The risk of cross contamination between runs belongs to the past and time-consuming cleaning is no longer needed since the system will be disposed of after usage.

The AppliFlex ST differentiates from other single-use bioreactors by being a fully customizable stirred tank bioreactor. You can choose, or even design, the type and number of impellers, the number of liquid and gas additions and the type of sparger that are optimal for your process. No more unused ports with blindplugs, but an optimized bioreactor for your specific process development and R&D application.

Typical upstream bioprocessing optimization concentrates on media and strain optimization. The AppliFlex ST enters in a new area of upstream Bioprocess hardware optimization. The Custom AppliFlex ST allows for optimization of essential parameters on a small scale such as impeller and sparger configuration. This technology allows you to optimize your bioreactor, to maximize product yield of your bioprocess.

The 3D printing production technology guarantees complete reproducibility between the different bioreactors guaranteeing exact and identical conditions between runs. The AppliFlex ST offers the flexibility that you need for your specific bioprocess and comes is available for both cell culture and microbial applications.

Appliflex ST
Appliflex ST Assembly

The AppliFlex ST can be used as single units as well as parallel processing systems. The design of the AppliFlex ST is a scale down version of our larger laboratory scale systems guaranteeing an easy scale-up of your process from the 500 mL to the larger volume cultivations. The single-use system can be exchanged with a glass multi-use system whenever your process or workflow needs a different approach. Existing glass system can also be easily transferred to work with the AppliFlex ST single use bioreactor

Sensors are available in re-usable format. The re-usable AppliSens mini sensors with only 8 mm diameter are available for pH and Dissolved Oxygen. The LumiSens optical Dissolved Oxygen sensor is supplied with the AppliFlex ST. No time consuming polarization is required.

Water supply is not required to operate the AppliFlex ST, cooling and heating are done using electric elements, the condenser is cooled electrically as well.
The AppliFlex ST combined with the Applikon my-Control is a very compact bioreactor system. A meter of bench space can fit up to 4 systems. No expensive laminar flowhood is needed to operate the system, expect for operator handling.

The AppliFlex ST features a fully removable topplate, this allows operators to have easy access to the culture. Pouring into downstream processing vessels or other bioreactors has never been this easy. Optionally a closed lid is available which makes the vessel ready for transport, storage or freezing.

AppliFlex ST Topplate

ReseaChem GmbH
Pestalozzistrasse 16 • CH-3400 Burgdorf/Switzerland • nfrschmch • Tel: ++41 34 424 03 10 • Fax: ++41 34 424 03 12

ReseaChem GmbH
Pestalozzistrasse 16 • CH-3400 Burgdorf/Switzerland • nfrschmch
Tel: ++41 34 424 03 10 • Fax: ++41 34 424 03 12


ReseaChem GmbH
Pestalozzistrasse 16
CH-3400 Burgdorf/Switzerland
Tel: ++41 34 424 03 10
Fax: ++41 34 424 03 12

©2016 ReseaChem GmbH / all rights reserved.