Holographic And Fluorescence Microscopy. In One Single System.
The new Ovizio QMod microscopy module takes the accuracy & simplicity of cell analysis to the next level. Available as a kit, it can be fixed on the c-mount where the camera is usually attached to the microscope. The QMod system is a particularly convenient and fast solution for direct cell counting in transparent supports, from petri dishes, flasks and multi-well plates to multi-layer vessels.
Designed for high precision, the QMod module generates in real-time the holographic fingerprint of each cell enabling the user to select and observe cells individually, based on a pre-defined set of parameters. Operated with the OsOne software, scientists can now automatically scan multi-well vessels, trace changes, make the distinction between living and dead cells and can even eliminate debris. To offer the best resolution, the images acquired with the OsOne software can ultimately be refocused post-acquisition.
Furthermore, in combination with a fluorescence microscope, the QMod module makes it now possible to overlay your fluorescent signal with your hologram! This unique approach opens the door to even more applications, with for example: confirmation of the results achieved in a label free set-up without the need for sample preparation, reagents and cell fixation. Applying the same device and sample, this method avoids the creation of toxic waste.
Combining Data Acquisition And Analysis with Machine Learning
The OsOne software is at the center of Ovizio's microscopes. Designed to deliver an optimal and delightful user experience, OsOne is built for easy data acquisition and thorough quantitative data analysis. The intuitive interface and wizard enable a rapid understanding and navigation of the app, providing a solid connection between the user and the device.
Cell density and viability are measured and reported in nearly real-time by using a label-free method based on the holographic fingerprint of cells. Cell confluency is indicated as the percentage of surface covered with cells. For a more in-depth monitoring, each individual cell can be observed and analyzed. A simple click on the image or in the dot plot simultaneously shows all data linked to that particular cell (diameter, perimeter, surface, circularity, intensity, aggregate size...).
Pestalozzistrasse 16 • CH-3400 Burgdorf/Switzerland • nfrschmch • Tel: ++41 34 424 03 10 • Fax: ++41 34 424 03 12
Pestalozzistrasse 16 • CH-3400 Burgdorf/Switzerland • nfrschmch
Tel: ++41 34 424 03 10 • Fax: ++41 34 424 03 12
Tel: ++41 34 424 03 10
Fax: ++41 34 424 03 12
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